Best PEEP trials are dependent on tidal volume

Best PEEP trials are dependent on tidal volume

Blog Article

Abstract Determining the optimal positive end-expiratory pressure (PEEP) in patients with acute respiratory distress syndrome remains an area of active investigation.Most sara stedy stand aid trials individualizing PEEP optimize one physiologic parameter (e.g.

, driving pressure) by titrating PEEP while holding other ventilator settings constant.Optimal PEEP, however, may depend on the tidal volume, and changing the tidal volume with which a best PEEP trial is performed may lead to different best PEEP settings pentair hose in the same patient.Trial registration ClinicalTrials.

gov, NCT02871102.Registered on 12 August 2016.